NLRP11 Rabbit Polyclonal Antibody
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USD 200.00
Other products for "NLRP11"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB,1:500 - 1:2000 IF,1:50 - 1:200 |
Reactivities | Human |
Modifications | Unmodified |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 420-600 of human NLRP11 (NP_659444.2). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 105kDa/111kDa/117kDa |
Gene Name | NLR family, pyrin domain containing 11 |
Database Link | |
Background | This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms. |
Synonyms | CLR19.6; FLJ26273; NALP11; NOD17; PAN10; PYPAF6; PYPAF7 |
Reference Data |
Documents
Product Manuals |
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