NCR1 Rabbit Polyclonal Antibody

CAT#: TA373045

NCR1 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: SKOV3 cell lysate Primary antibody: TA373045 (NCR1 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: SKOV3 cell lysate
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human NCR1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 34 kDa
• Gene Name: natural cytotoxicity triggering receptor 1
• Database Link:
  Entrez Gene 9437 Human
  UniProt ID O76036
• Background: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.When LY94 is expressed in COS-7 cells, anti-NKp46 immunoprecipitates a 46-kD surface molecule. Northern blot analysis revealed weak expression of a major transcript of 3.4 kb in spleen but in no other human tissue. Further analysis, with RT-PCR confirmation, in various lymphoid and myelomonocytic cells revealed that LY94 expression is confined to NK cells.
• Synonyms: CD335; FLJ99094; hNKp46; LY94; NK-p46; NKP46