ALPK2 Rabbit Polyclonal Antibody

CAT#: TA371848

ALPK2 rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA371848 (ALPK2 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA371848 (ALPK2 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 20-100
  Positive control: Human colorectal cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human ALPK2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Gene Name: alpha kinase 2
• Database Link:
  Entrez Gene 115701 Human
  UniProt ID Q86TB3
• Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. å-protein kinase 2, also known as ALPK2 or HAK (Heart alpha-protein kinase), is a 2,170 amino acid member of the protein kinase superfamily and contains one å-type protein kinase domain and one Ig-like domain. Expressed at higher levels in heart tissue, å-protein kinase 2 recognizes and phosphorylates specific phosphorylation sites that are surrounded by peptides which have an å-helical conformation, possibly playing a role in vesicle trafficking.
• Synonyms: FLJ34875; FLJ43253; HAK