FRMD5 Rabbit Polyclonal Antibody

CAT#: TA370949

FRMD5 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-2: HUVEC cell Mouse kidney tissue lysates Primary antibody: TA370949 (FRMD5 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 3 minutes

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA370949 (FRMD5 Antibody) at dilution 1/160 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA370949 (FRMD5 Antibody) at dilution 1/160, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: HUVEC cell, Mouse kidney tissue lysates
  IHC: 150-300
  Positive control: Human thyroid cancer
  Predicted cell location: Cell membrane
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human FRMD5
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 65 kDa
• Gene Name: FERM domain containing 5
• Database Link:
  Entrez Gene 84978 Human
  UniProt ID Q7Z6J6
• Background: May be involved in regulation of cell migration (PubMed:22846708, PubMed:25448675). May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation (PubMed:25448675).
• Synonyms: FLJ41022; MGC14161