MYG1 Rabbit Polyclonal Antibody

CAT#: TA369854

C12orf10 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-3: PC-3 MCF-7 and 293T cell lysates Primary antibody: TA369854 (C12orf10 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA369854 (C12orf10 Antibody) at dilution 1/35 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA369854 (C12orf10 Antibody) at dilution 1/35, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA369854 (C12orf10 Antibody) at dilution 1/35 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA369854 (C12orf10 Antibody) at dilution 1/35, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: PC-3,MCF-7 and 293T cell lysates
  IHC: 25-100
  Positive control: Human esophagus cancer
  Predicted cell location: Nucleus and Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human C12orf10
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 42 kDa
• Gene Name: chromosome 12 open reading frame 10
• Database Link:
  Entrez Gene 60314 Human
  UniProt ID Q9HB07
• Background: C12orf10, also known as MYG1, MYG1 is a 376 amino acid nucleo-mitochondrial protein belonging to the UPF0160 (MYG1) family. MYG1 is encoded by a gene that maps to human chromosome 12q13.13 and is ubiquitously expressed in simple as well as complex eukaryotes, with highest levels in testis. Considered to have a metal-dependent protein hydrolase (UPF0160) domain, MYG1 exhibits a mitochondrial targeting signal in the N-terminal region and a Pat7-type nuclear localization signal in the region between amino acids 33-39. Although MYG1 displays differential patterns and levels of expression during embryonic development, expression in normal adult tissues is stable, suggesting MYG1 involvement in early developmental processes and in adult stress/illness conditions. Elevation of MYG1 expression may be also associated with vitiligo susceptibility.
• Synonyms: MST024; MSTP024; MYG; MYG1