PAS1C1 (LMNTD1) Rabbit Polyclonal Antibody

CAT#: TA369525

LMNTD1 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: HEPG2 cell lysate Primary antibody: TA369525 (LMNTD1 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA369525 (LMNTD1 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA369525 (LMNTD1 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: HEPG2 cell lysate
  IHC: 10-50
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human LMNTD1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 43 kDa
• Gene Name: lamin tail domain containing 1
• Database Link:
  Entrez Gene 160492 Human
  UniProt ID Q8N9Z9
• Background: LMNTD1, also known as IFLTD1. IFLTD1 was initially identified as a candidate gene for pulmonary adenoma susceptibility 1 gene in mice. Transcripts of the gene were only detected in mouse lung tissue from strains carrying the Pas1-susceptible allele. Expression of different alleles of this gene in lung cancer cell lines resulted in different levels of colony formation in in vitro colony formation assays, suggesting that allelic variants of this gene can modulate growth of human cancer cells.