VPS18 Rabbit Polyclonal Antibody

CAT#: TA368894

VPS18 rabbit polyclonal antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-2: Hela and K562 cell lysates Primary antibody: TA368894 (VPS18 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 50 seconds

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA368894 (VPS18 Antibody) at dilution 1/35. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Hela and K562 cell lysates
  IHC: 25-100
  Positive control: Human gastric cancer
  Predicted cell location: Cytoplasm and Cell membrane
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human VPS18
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 110 kDa
• Gene Name: VPS18, CORVET/HOPS core subunit
• Database Link:
  Entrez Gene 57617 Human
  UniProt ID Q9P253
• Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
• Synonyms: hVPS18; KIAA1475; PEP3