Glycoprotein VI (GP6) Rabbit Polyclonal Antibody

CAT#: TA368380

GP6 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-3: K562 Jurkat and 293T cell lysates Primary antibody: TA368380 (GP6 Antibody) at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 minutes

• 

  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA368380 (GP6 Antibody) at dilution 1/50 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA368380 (GP6 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA368380 (GP6 Antibody) at dilution 1/50 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA368380 (GP6 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: K562,Jurkat and 293T cell lysates
  IHC: 50-300
  Positive control: Human colorectal cancer
  Predicted cell location: Cell membrane
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human GP6
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 37 kDa
• Gene Name: glycoprotein VI platelet
• Database Link:
  Entrez Gene 51206 Human
  UniProt ID Q9HCN6
• Background: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Synonyms: GPIV; GPVI; MGC138168