PCBD1 Rabbit Polyclonal Antibody

CAT#: TA366340

PCBD1 rabbit polyclonal antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Human fetal liver tissue lysate Primary antibody: TA366340 (PCBD1 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 30 seconds

• 

  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA366340 (PCBD1 Antibody) at dilution 1/90 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA366340 (PCBD1 Antibody) at dilution 1/90, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA366340 (PCBD1 Antibody) at dilution 1/90 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA366340 (PCBD1 Antibody) at dilution 1/90, treated with fusion protein. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human fetal liver tissue lysate
  IHC: 80-400
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human PCBD1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 12 kDa
• Gene Name: pterin-4 alpha-carbinolamine dehydratase 1
• Database Link:
  Entrez Gene 5092 Human
  UniProt ID P61457
• Background: This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
• Synonyms: DCoH; PCBD; PCD; PHS