TSEN2 Rabbit Polyclonal Antibody

CAT#: TA366289

TSEN2 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Human fetal brain tissue lysate Primary antibody: TA366289 (TSEN2 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 10 minutes

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA366289 (TSEN2 Antibody) at dilution 1/80 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA366289 (TSEN2 Antibody) at dilution 1/80, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA366289 (TSEN2 Antibody) at dilution 1/80 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA366289 (TSEN2 Antibody) at dilution 1/80, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Human fetal brain tissue lysate
  IHC: 50-300
  Positive control: Human esophagus cancer
  Predicted cell location: Nucleus and Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human TSEN2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 53 kDa
• Gene Name: tRNA splicing endonuclease subunit 2
• Database Link:
  Entrez Gene 80746 Human
  UniProt ID Q8NCE0
• Background: This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: HsSen2; MGC2776; MGC4440; OTTHUMP00000207749; PCH2B; SEN2; SEN2L