cIAP2 (BIRC3) Rabbit Polyclonal Antibody

CAT#: TA364562

BIRC3 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Raji cell lysate Primary antibody: TA364562 (BIRC3 Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 2 minutes

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA364562 (BIRC3 Antibody) at dilution 1/130 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA364562 (BIRC3 Antibody) at dilution 1/130, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA364562 (BIRC3 Antibody) at dilution 1/130 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA364562 (BIRC3 Antibody) at dilution 1/130, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Raji cell lysate
  IHC: 100-200
  Positive control: Human esophagus cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human BIRC3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 68 kDa
• Gene Name: baculoviral IAP repeat containing 3
• Database Link:
  Entrez Gene 330 Human
  UniProt ID Q13489
• Background: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
• Synonyms: AIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP-1; HIAP1; IAP1; MALT2; MIHC; RNF49