GLP1 (GCG) Rabbit Polyclonal Antibody

CAT#: TA364306

Rabbit polyclonal anti Oxyntomodulin (glucagon-37) (hu, ms, rt); diluted antiserum

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Oxyntomodulin. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys- Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn- Thr-Lys-Arg-Asn-Arg-Asn-Asn-Ile-Ala-OH coupled to carrier protein.
• Formulation: Each vial contains enough antiserum for 500 RIA tubes. The powder should be rehydrated with 50ml RIA buffer. Upon reconstitution to 50ml total volume, the solution contains 0.1M sodium phosphate buffer (pH 7.4), 0.05M NaCl, 0.1% BSA, 0.01% NaN3, and 0.1% Triton X-100. Store at 4°C. This should ensure antibody stability for approximately one month.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: glucagon
• Database Link:
  Entrez Gene 2641 Human
  UniProt ID P01275
• Background: Oxyntomodulin (OXM) a 37-amino acid peptide hormone found in the colon, produced by the oxyntic cells of the oxyntic mucosa. It is known to suppress appetite and causes weight loss in humans and rodents. Oxyntomodulin activates both the glucagon-like peptide-1 receptor (GLP1R) and the glucagon receptor (GCGR). It contains the same sequence as Glucagon (1-29), but with an additional KRNKNNIA C-terminal sequence. This antibody was generated by immunization of rabbits with Oxyntomodulin coupled to a carrier protein.
• Synonyms: GLP1; GLP2; glucagon; GRPP