GLP1 (GCG) Rabbit Polyclonal Antibody

CAT#: TA364304

Rabbit polyclonal anti Oxyntomodulin (glucagon-37) (human, mouse, rat) - Purified Antiserum - IgG,

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Oxyntomodulin. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys- Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn- Thr-Lys-Arg-Asn-Arg-Asn-Asn-Ile-Ala-OH coupled to carrier protein.
• Formulation: Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: glucagon
• Database Link:
  Entrez Gene 2641 Human
  UniProt ID P01275
• Background: Oxyntomodulin (OXM) a 37-amino acid peptide hormone found in the colon, produced by the oxyntic cells of the oxyntic mucosa. It is known to suppress appetite and causes weight loss in humans and rodents. Oxyntomodulin activates both the glucagon-like peptide-1 receptor (GLP1R) and the glucagon receptor (GCGR). It contains the same sequence as Glucagon (1-29), but with an additional KRNKNNIA C-terminal sequence. This antibody was generated by immunization of rabbits with Oxyntomodulin coupled to a carrier protein.
• Synonyms: GLP1; GLP2; glucagon; GRPP