Ptbp1 Rabbit Polyclonal Antibody

CAT#: TA363071

PTBP1 Antibody - middle region

Product Images

Host: Rabbit Target Name: PTBP1 Sample Tissue: Mouse Heart lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse PTBP1
• Specificity: Expected reactivity: Mouse
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 57 kDa
• Gene Name: polypyrimidine tract binding protein 1
• Database Link:
  Entrez Gene 19205 Mouse
  UniProt ID P17225
• Background: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.
• Synonyms: HNRNP-I; HNRNPI; HNRPI; MGC8461; MGC10830; pPTB; PTB; PTB-1; PTB-T; PTB2; PTB3; PTB4