SETMAR Rabbit Polyclonal Antibody

CAT#: TA362681

SETMAR Antibody - middle region

Product Images

Host: Rabbit Target Name: SETMAR Sample Tissue: Human PANC1 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SETMAR
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 41 kDa
• Gene Name: SET domain and mariner transposase fusion gene
• Database Link:
  NP_001230652.1
  Entrez Gene 6419 Human
  UniProt ID Q53H47-2
• Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
• Synonyms: Hsmar1; METNASE

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Lysine degradation