APPL (APPL1) Rabbit Polyclonal Antibody

CAT#: TA362633

APPL1 Antibody - middle region

Product Images

Host: Rabbit Target Name: APPL1 Sample Tissue: Human Jurkat Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human APPL1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 80 kDa
• Gene Name: adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
• Database Link:
  NP_036228.1
  Entrez Gene 26060 Human
  UniProt ID Q9UKG1
• Background: The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
• Synonyms: APPL; Dip13-alpha; DIP13A; DIP13alpha; KIAA1428

Reference Data

• Protein Pathways: Colorectal cancer, Pathways in cancer