ERp19 (TXNDC12) Rabbit Polyclonal Antibody

CAT#: TA360664

TXNDC12 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: TXNDC12 Sample Tissue: Human Large Intestine Tumor lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TXNDC12
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 18 kDa
• Gene Name: thioredoxin domain containing 12
• Database Link:
  NP_056997
  Entrez Gene 51060 Human
  UniProt ID O95881
• Background: This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.
• Synonyms: AG1; AGR1; ERP18; ERP19; hAG-1; hTLP19; PDIA16; TLP19

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Glutathione metabolism