HPS2 (AP3B1) Rabbit Polyclonal Antibody

CAT#: TA360263

AP3B1 Antibody - middle region

Product Images

Host: Rabbit Target Name: AP3B1 Sample Tissue: Human PANC1 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AP3B1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 120 kDa
• Gene Name: adaptor related protein complex 3 beta 1 subunit
• Database Link:
  NP_001258698.1
  Entrez Gene 8546 Human
  UniProt ID O00203
• Background: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: ADTB3; ADTB3A; beta3A-adaptin; HPS; HPS2; PE

Reference Data

• Protein Pathways: Lysosome