STAM2 Rabbit Polyclonal Antibody

CAT#: TA359853

STAM2 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: STAM2 Sample Tissue: Human HT1080 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STAM2
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 58 kDa
• Gene Name: signal transducing adaptor molecule 2
• Database Link:
  NP_005834.4
  Entrez Gene 10254 Human
  UniProt ID O75886
• Background: The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
• Synonyms: DKFZp564C047; Hbp; STAM-2; STAM2A; STAM2B

Reference Data

• Protein Pathways: Endocytosis, Jak-STAT signaling pathway