MMP1 Rabbit Polyclonal Antibody

CAT#: TA356169

MMP1 Antibody - N-terminal region

Product Images

Sample Type: Equine Cartilage Explants Primary Dilution: 1:800 Secondary Antibody: Bio-Rad 170-5046 Secondary Dilution::100,000 Image Submitted By: Adam Williams University of Nottingham

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  WB Suggested Anti-MMP1 Antibody Positive Control: Lane 1: 15ug HT29 cell lysate Lane 2: 15ug HT29 cell lysate Primary Antibody Dilution : 1:500 Secondary Antibody : Anti-rabbit-HRP Secondry Antibody Dilution : 1:2000 Submitted by: Zhongsheng Peng, School of Medicine, University of Maryland Baltimore

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  Host: Rabbit Target Name: MMP1 Sample Tissue: Human 293T Antibody Dilution: 1.0ug/ml

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  species sample : Human cell/tissue : macrophagesHuman macrophages dilution : 1/200

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  Rabbit Anti-MMP1 Antibody Catalog Number: ARP42039 Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X

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  MMP1 in epithelial cells ovarian carcinoma was detected using HRP/DAB brown color stain. Antibody Titration: 2-10ug/ml Positive Control: Human epithelial cells ovarian carcinoma

• Human Colorectal cancer sample Human Liver Sample

• Rabbit Anti-MMP1 Antibody Catalog Number: ARP42039 Paraffin Embedded Tissue: Human alveolar cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X

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Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human, Horse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MMP1
• Specificity: Expected reactivity: Horse, Human
  Homology: Horse: 77%; Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 54kDa
• Gene Name: matrix metallopeptidase 1
• Database Link:
  NP_002412
  Entrez Gene 4312 Human
  UniProt ID P03956
• Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP1 is a secreted enzyme which breaks down the interstitial collagens, types I, II, and III.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
• Synonyms: CLG; CLGN; MMP-1

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Bladder cancer, Pathways in cancer, PPAR signaling pathway