Nav1.6 (SCN8A) Rabbit Polyclonal Antibody

CAT#: TA355747

SCN8A Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: SCN8A Sample Type: Fetal Heart lysates Antibody Dilution: 1.0ug/ml

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  WB Suggested Anti-SCN8A antibody Titration: 1 ug/mL Sample Type: Human heart

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  Rabbit Anti-SCN8A Antibody Catalog Number: TA355747 Formalin Fixed Paraffin Embedded Tissue: Human Adult heart Observed Staining: Membrane Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5–2.0 sec Protocol located in Reviews and Data.

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  Rabbit Anti-SCN8A Antibody Catalog Number: TA355747 Formalin Fixed Paraffin Embedded Tissue: Human Adult liver Observed Staining: Membrane Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5–2.0 sec Protocol located in Reviews and Data.

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SCN8A
• Specificity: Expected reactivity: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 52kDa
• Gene Name: sodium voltage-gated channel alpha subunit 8
• Database Link:
  NP_001171455.1
  Entrez Gene 6334 Human
  UniProt ID Q9UQD0
• Background: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
• Synonyms: CerIII; MED; NaCh6; Nav1.6; PN4

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Sodium, Transmembrane