Ku70 (XRCC6) Rabbit Polyclonal Antibody

CAT#: TA355655

G22P1 Antibody - N-terminal region

Product Images

WB Suggested Anti-G22P1 Antibody Titration: 0.6ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysateXRCC6 is supported by BioGPS gene expression data to be expressed in HepG2

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  Human Liver

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  Human kidney

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  Rabbit Anti-XRCC6 Antibody Catalog Number: ARP34117 Paraffin Embedded Tissue: Human cardiac cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human G22P1
• Specificity: Expected reactivity: Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
  Homology: Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 70kDa
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 6
• Database Link:
  NP_001460
  Entrez Gene 2547 Human
  UniProt ID Q6FG89
• Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
• Synonyms: CTC75; CTCBF; D22S671; D22S731; G22P1; KU70; ML8; OTTHUMP00000199333; OTTHUMP00000199349; TLAA

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Non-homologous end-joining