Parathyroid Hormone (PTH) Mouse Monoclonal Antibody [Clone ID: 105G7]

CAT#: TA355331

Parathyroid Hormone (PTH) Mouse Monoclonal Antibody

Product Images

Human parathyroid adenoma: immunohistochemical staining for Parathyroid Hormone. Parathyroid Hormone: clone 105G7

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  Human parathyroid adenoma: immunohistochemical staining for Parathyroid Hormone. Parathyroid Hormone: clone 105G7

Specifications

Product Data

• Clone Name: 105G7
• Applications: IHC
• Recommended Dilution: 1:300
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant protein corresponding to the entire human parathyroid hormone molecule
• Specificity: Human parathyroid hormone
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: parathyroid hormone
• Database Link:
  Entrez Gene 5741 Human
  UniProt ID P01270
• Background: The parathyroid glands are small, oval, endocrine glands closely associated with the thyroid gland. The parathyroid glands regulate serum calcium and phosphate levels via parathyroid hormone (parathormone). Parathyroid hormone raises serum calcium levels directly, by increasing the rate of osteoclastic reabsorption and promoting breakdown of the bone matrix, and indirectly, by increasing the renal tubular reabsorption of calcium ions and inhibiting the reabsorption of phosphate ions from the glomerular filtrate, and finally, by promoting the absorption of calcium from the small intestine. Parathyroid hormone is the most important regulator of blood calcium levels and is essential to life, whereas calcitonin appears only to provide a complementary mechanism for fine adjustment. Chief cells are the most abundant cells in the parathyroid gland and are responsible for the secretion of parathyroid hormone.
• Synonyms: parathormone; Parathyrin; PTH1