Myosin Heavy Chain (developmental) Mouse Monoclonal Antibody [Clone ID: RNMy2/9D2]

CAT#: TA355321

Myosin Heavy Chain (developmental) Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: RNMy2/9D2
• Applications: IHC
• Recommended Dilution: 1:10 - 1:40
• Reactivities: Human, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Native myosin extracted from the hind limb muscle of 7 day old rats
• Specificity: Human myosin developmental type heavy chain. Note that this antibody recognises a myosin heavy chain (MHC) present during the embryonic and neonatal period in the development of skeletal muscle. The same MHC occurs during regeneration of muscle fibres. Also reacts with rat myosin developmental type heavy chain.
• Formulation: Lyophilized tissue culture supernatant containing 15 mM sodium azide as a preservative.
• Reconstitution Method: The user is required to reconstitute the contents of the vial with the correct volume of sterile distilled water as indicated on the vial label
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Background: Myosin is a contractile muscle specific protein composed of two heavy and four light chains. The myosin heavy chain has many isoforms which are specific for different muscles or fiber types, some of which are developmentally regulated. The range of myosin heavy chain antibodies may prove useful for investigating development of intrafusal and extrafusal muscle fibers and the course of muscle fiber regeneration. At the ultrastructural level, antibodies can reveal architectural details of the myofilament as well as the cytoplasmic and membrane sites of new myosin integration.