CAMKIV (CAMK4) Rabbit Polyclonal Antibody

CAT#: TA354322

Rabbit anti CaM Kinase IV Polyclonal Antibody

Product Images

IHC: Human brain stained with anti-CaM Kinase IV antibody at 1:100 for 30 min, RT. (Staining of formalin-fixed tissues requires boiling tissue section in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20min.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC Not tested
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide from aa 457-474 of rat CaM Kinase IV.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 65 kDa
• Gene Name: calcium/calmodulin-dependent protein kinase IV
• Database Link:
  NP_001735
  Entrez Gene 25050 RatEntrez Gene 814 Human
  UniProt ID Q16566
• Background: Calmodulin dependent protein kinases (CaM kinases) consist of a family of Ser/Thr protein kinases including CaMKI, CaMKII and CaMKIV. CaMKs are considered to play a central role in many cellular functions in response to Ca2+ signaling, including synthesis and secretion of neurotransmitters, axonal transport, long term potentiation etc. CaM kinase IV is abundantly expressed in the brain, in the thymus, and is localized to the cytoplasm and nucleus.
• Synonyms: caMK; CaMK-GR; CaMK IV; IV

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Calcium signaling pathway, Long-term potentiation, Neurotrophin signaling pathway