PON1 Rabbit Polyclonal Antibody

CAT#: TA351548

Rabbit Polyclonal Anti-PON1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-5: Hela cells skov3 cells A549 cells mouse liver tissue human ovarian cancer tissue Primary antibody: TA351548 (PON1 Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA351548 (PON1 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA351548 (PON1 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351548 (PON1 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351548 (PON1 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Hela, skov3 and A549 cells, mouse liver and human ovarian cancer tissue
  IHC: 50-200
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PON1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40 kDa
• Gene Name: paraoxonase 1
• Database Link:
  NP_000437
  Entrez Gene 84024 RatEntrez Gene 5444 Human
  UniProt ID P27169
• Background: The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
• Synonyms: ESA; MVCD5; PON

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Metabolic pathways