NDUFAB1 Rabbit Polyclonal Antibody

CAT#: TA351431

Rabbit Polyclonal Anti-NDUFAB1 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA351431 (NDUFAB1 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA351431 (NDUFAB1 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA351431 (NDUFAB1 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA351431 (NDUFAB1 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 100-300
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human NDUFAB1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: NADH:ubiquinone oxidoreductase subunit AB1
• Database Link:
  NP_004994
  Entrez Gene 4706 Human
  UniProt ID O14561
• Background: NDUFAB1 (NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1), also known as SDAP, ACP (acyl carrier protein) or FASN2A, is one of about 45 subunits comprising Complex I of the oxidative phosphorylation electron transport chain. Consisting of 156 amino acids and localizing to mitochondria, NDUFAB1 functions as an accessory subunit of the multi-protein mitochondrial membrane respiratory chain NADH dehydrogenase complex (known as Complex I). Complex I plays an important role in the transfer of electrons from NADH to the respiratory chain, a process that is essential for cellular respiration. NDUFAB1 contains one acyl carrier domain and is encoded by a gene that maps to human chromosome 16p12.2 and mouse chromosome 7 F3.
• Synonyms: ACP; FASN2A; SDAP

Reference Data

• Protein Pathways: Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease