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Monoacylglycerol Lipase (MGLL) Rabbit Polyclonal Antibody
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USD 436.00
USD 200.00
USD 867.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm and Nucleus |
| Reactivities | Human |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MGLL |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | monoglyceride lipase |
| Database Link | |
| Background | This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Synonyms | HU-K5; HUK5; MAGL; MGL |
| Reference Data | |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Glycerolipid metabolism, Metabolic pathways |
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