Upstream Binding Protein 1 (UBP1) Rabbit Polyclonal Antibody

CAT#: TA351346

Rabbit Polyclonal Anti-UBP1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: PC3 cells Primary antibody: TA351346 (UBP1 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA351346 (UBP1 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA351346 (UBP1 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: PC3 cells
  IHC: 50-200
  Positive control: Human cervical cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human UBP1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 60 kDa
• Gene Name: upstream binding protein 1 (LBP-1a)
• Database Link:
  NP_055332
  Entrez Gene 22221 MouseEntrez Gene 7342 Human
  UniProt ID Q9NZI7
• Background: LBP1 (Upstream-binding protein 1), also designated UBP1, LBP1A or LBP1B, is a 540 amino acid protein that belongs to the grh/CP2 family (grainyhead transcription factor family). LBP1 is a transcriptional activator that regulates the placental expression of CYP11A1 and activates the Hemoglobin globin promoter in erythroid cells. LBP1 is responsible for repressing transcription of HIV-1 by binding to and preventing TFIID from interacting with its promoter region. expression of LBP1 causes uterine growth retardation in mice embryos suggesting a critical role in extraembryonic angiogenesis.
• Synonyms: LBP-1a; LBP-1B; LBP1A; LBP1B

Reference Data

• Protein Families: Transcription Factors