TFII I (GTF2I) Rabbit Polyclonal Antibody

CAT#: TA351003

Rabbit Polyclonal Anti-GTF2I Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: HepG2 cells Primary antibody: TA351003 (GTF2I Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 3 minutes

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA351003 (GTF2I Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA351003 (GTF2I Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA351003 (GTF2I Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA351003 (GTF2I Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: HepG2 cells
  IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human GTF2I
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 112 kDa
• Gene Name: general transcription factor IIi
• Database Link:
  NP_127492
  Entrez Gene 14886 MouseEntrez Gene 353256 RatEntrez Gene 2969 Human
  UniProt ID P78347
• Background: This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
• Synonyms: BAP135; BTKAP1; DIWS; GTFII-I; IB291; SPIN; TFII-I; WBS; WBSCR6

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Basal transcription factors