ARL3 Rabbit Polyclonal Antibody

CAT#: TA350990

Rabbit Polyclonal Anti-ARL3 Antibody

Product Images

Gel: 15%SDS-PAGE Lysate: 40 μg Lane 1-3: Mouse brain tissue 231 cells A375 cells Primary antibody: TA350990 (ARL3 Antibody) at dilution 1/433 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Mouse brain tissue and 231 cells, A375 cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human ARL3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20 kDa
• Gene Name: ADP ribosylation factor like GTPase 3
• Database Link:
  NP_004302
  Entrez Gene 403 Human
  UniProt ID P36405
• Background: ADP-ribosylation factor-like 3 is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL3 binds guanine nucleotides but lacks ADP-ribosylation factor activity. Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms.
• Synonyms: ARFL3

Reference Data

• Protein Families: Druggable Genome