Fos B (FOSB) Rabbit Polyclonal Antibody

CAT#: TA350663

Rabbit Polyclonal Anti-FOSB Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-3: Human kidney cancer tissue Human lung cancer tissue human placenta tissue Primary antibody: TA350663 (FOSB Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 minutes

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA350663 (FOSB Antibody) at dilution 1/20 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA350663 (FOSB Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA350663 (FOSB Antibody) at dilution 1/20 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA350663 (FOSB Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human kidney cancer and lung cancer tissue, human placenta tissue
  IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human FOSB
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 36 kDa
• Gene Name: FosB proto-oncogene, AP-1 transcription factor subunit
• Database Link:
  NP_006723
  Entrez Gene 14282 MouseEntrez Gene 2354 Human
  UniProt ID P53539
• Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: AP-1; G0S3; GOS3; GOSB

Reference Data

• Protein Families: Druggable Genome, Transcription Factors