SWAP70 Rabbit Polyclonal Antibody

CAT#: TA350580

Rabbit Polyclonal Anti-SWAP70 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human brain tissue using TA350580 (SWAP70 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA350580 (SWAP70 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA350580 (SWAP70 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA350580 (SWAP70 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 10-50
  Positive control: Human brain
  Predicted cell location: Cytoplasm or Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human SWAP70
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SWAP switching B-cell complex 70kDa subunit
• Database Link:
  NP_055870
  Entrez Gene 20947 MouseEntrez Gene 23075 Human
  UniProt ID Q9UH65
• Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).
• Synonyms: HSPC321; SWAP-70