MTP18 (MTFP1) Rabbit Polyclonal Antibody

CAT#: TA350191

Rabbit Polyclonal Anti-MTFP1 Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Mouse heart tissue lysate Primary antibody: TA350191 (MTFP1 Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 7 seconds

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA350191 (MTFP1 Antibody) at dilution 1/80 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA350191 (MTFP1 Antibody) at dilution 1/80, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse heart tissue lysate
  IHC: 50-200
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human MTFP1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 18 kDa
• Gene Name: mitochondrial fission process 1
• Database Link:
  NP_001003704
  Entrez Gene 51537 Human
  UniProt ID Q9UDX5
• Background: MTP18 (mitochondrial 18 kDa protein), also known as HSPC242, is a 166 amino acid protein essential for cell viability. MTP18 may also have a role in maintaining the integrity of the mitochondrial network. Localized to the mitochonrion, expression of MTP18 is regulated by the PI 3-kinase pathway. Loss of function of MTP18 results in the release of cytochrome c, which subsequently activates the caspase cascade and leads to apoptosis.
• Synonyms: HSPC242; MTP18