Estrogen Related Receptor gamma (ESRRG) Rabbit Polyclonal Antibody

CAT#: TA349941

Rabbit Polyclonal Anti-ESRRG Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Mouse lung tissue Primary antibody: TA349941 (ESRRG Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 40 seconds

• 

  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA349941 (ESRRG Antibody) at dilution 1/30 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA349941 (ESRRG Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349941 (ESRRG Antibody) at dilution 1/30 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349941 (ESRRG Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse lung tissue
  IHC: 50-200
  Positive control: Human gasrtic cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ESRRG
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51 kDa
• Gene Name: estrogen related receptor gamma
• Database Link:
  NP_001429
  Entrez Gene 26381 MouseEntrez Gene 360896 RatEntrez Gene 2104 Human
  UniProt ID P62508
• Background: This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways.
• Synonyms: ERR3; ERRgamma; NR3B3

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors