G protein alpha 13 (GNA13) Rabbit Polyclonal Antibody

CAT#: TA349321

Rabbit Polyclonal Anti-GNA13 Antibody

Product Images

Gel: 15%SDS-PAGE Lysate: 40 μg Lane 1-5: A172 cells 293T cells mouse kidney tissue human testis tissue Human brain malignant glioma tissue Primary antibody: TA349321 (GNA13 Antibody) at dilution 1/600 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA349321 (GNA13 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA349321 (GNA13 Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA349321 (GNA13 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA349321 (GNA13 Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: A172 and 293T cells, mouse kidney tissue, human testis and brain malignant glioma tissue
  IHC: 50-200
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human GNA13
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 44 kDa
• Gene Name: G protein subunit alpha 13
• Database Link:
  NP_006563
  Entrez Gene 14674 MouseEntrez Gene 303634 RatEntrez Gene 10672 Human
  UniProt ID Q14344
• Background: Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the GNA13gene. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5. Interacts with HAX1. Interacts (when active) with PPP5C (via TPR repeats); activates PPP5C phosphatase activity and translocates PPP5C to the cell membrane.
• Synonyms: G13

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Long-term depression, Regulation of actin cytoskeleton, Vascular smooth muscle contraction