FASTK Rabbit Polyclonal Antibody

CAT#: TA349317

Rabbit Polyclonal Anti-FASTK Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA349317 (FASTK Antibody) at dilution 1/30. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA349317 (FASTK Antibody) at dilution 1/30. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human gasrtic cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human FASTK
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Fas activated serine/threonine kinase
• Database Link:
  NP_148936
  Entrez Gene 66587 MouseEntrez Gene 10922 Human
  UniProt ID Q14296
• Background: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
• Synonyms: FAST

Reference Data

• Protein Families: Druggable Genome, Protein Kinase