IKB beta (NFKBIB) Rabbit Polyclonal Antibody

CAT#: TA349227

Rabbit Polyclonal Anti-NFKBIB Antibody

Product Images

Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Jurkat cells, MCF7 cells, hela cells, Primary antibody: (NFKBIB Antibody) at dilution 1/1050, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 2000-5000, WB: 500-2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human NFKBIB
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: NFKB inhibitor beta
• Database Link:
  NP_002494
  Entrez Gene 4793 Human
  UniProt ID Q15653
• Background: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: IKBB; TRIP9

Reference Data

• Protein Families: Stem cell - Pluripotency, Transcription Factors
• Protein Pathways: Adipocytokine signaling pathway, B cell receptor signaling pathway, Chemokine signaling pathway, Cytosolic DNA-sensing pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway