Density Regulated Protein (DENR) Rabbit Polyclonal Antibody

CAT#: TA349040

Rabbit Polyclonal Anti-DENR Antibody

Product Images

Western blot analysis of DENR in human brain tissue lysate with DENR antibody at 1 ug/mL.

• 

  Immunohistochemistry of DENR in rat brain tissue with DENR antibody at 5 ug/mL.

• 

  Immunofluorescence of DENR in rat brain tissue with DENR antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DENR antibody was raised against an 18 amino acid peptide near the center of human DENR.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: DENR antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 22 kDa; Observed: 22 kDa
• Gene Name: density-regulated protein
• Database Link:
  NP_003668
  Entrez Gene 8562 Human
  UniProt ID O43583
• Background: DENR (density-regulated protein), also designated DRP or smooth muscle cell associated protein 3 (SMAP-3), is a 198 amino acid protein that may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon (1). It plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 (2,3). DENR contains a SUI1 domain and is found in a variety of tissues with highest levels present in skeletal and cardiac muscle. It is up-regulated in ovarian and breast cancer cells by ERBB2 overexpression (4).
• Synonyms: HSST2; NST2