GAS41 (YEATS4) Rabbit Polyclonal Antibody

CAT#: TA347600

Rabbit Polyclonal Anti-GAS41 Antibody

Product Images

Western blot analysis on mouse lung cell lysate using GAS41 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-GAS41 Antibody: A synthesized peptide derived from human GAS41
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40 kDa
• Gene Name: YEATS domain containing 4
• Database Link:
  NP_006521
  Entrez Gene 64050 MouseEntrez Gene 8089 Human
  UniProt ID O95619
• Background: YEATS4 Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
• Synonyms: 4930573H17Rik; B230215M10Rik; GAS41; NUBI-1; YAF9
• Note: GAS41 Antibody detects endogenous levels of GAS41

Reference Data

• Protein Families: Druggable Genome, Transcription Factors