PTPN22 Rabbit Polyclonal Antibody

CAT#: TA347579

Rabbit Polyclonal Anti-PTPN22 Antibody

Product Images

Western blot analysis on HeLa cell lysate using PTPN22 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-PTPN22 Antibody: A synthesized peptide derived from human PTPN22
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 91 kDa
• Gene Name: protein tyrosine phosphatase, non-receptor type 22
• Database Link:
  NP_057051
  Entrez Gene 19260 MouseEntrez Gene 295338 RatEntrez Gene 26191 Human
  UniProt ID Q9Y2R2
• Background: PTPN22 Seems to act on Cbl. May play a role in regulating the function of Cbl and its associated protein kinases. Acts as negative regulator of T cell receptor (TCR) signaling. Dephosphorylates and inactivates the SRC family kinases. Belongs to the protein-tyrosine phosphatase family.
• Synonyms: LYP; LYP1; LYP2; PEP; PTPN8
• Note: PTPN22 antibody detects endogenous levels of total PTPN22

Reference Data

• Protein Families: Druggable Genome, Phosphatase