TXNRD2 Mouse Monoclonal Antibody [Clone ID: 3F2-E12-F10]

CAT#: TA347066

Mouse Monoclonal TXNRD2 Antibody

Specifications

Product Data

• Clone Name: 3F2-E12-F10
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for TXNRD2 antibody: purified recombinant human TXNRD2 protein fragments expressed in E.coli.
• Formulation: ascites
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 56 kDa
• Gene Name: thioredoxin reductase 2
• Database Link:
  NP_006431
  Entrez Gene 10587 Human
  UniProt ID Q9NNW7
• Background: Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22.
• Synonyms: SELZ; TR; TR-BETA; TR3; TRXR2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Pyrimidine metabolism