SIRT1 Mouse Monoclonal Antibody [Clone ID: 2G10-F4-D9]

CAT#: TA347045

Mouse Monoclonal SIRT1 Antibody

Specifications

Product Data

• Clone Name: 2G10-F4-D9
• Applications: IP, WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: The immunogen for SIRT1 antibody: purified recombinant human SIRT1 protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 120 kDa
• Gene Name: sirtuin 1
• Database Link:
  NP_001135970
  Entrez Gene 23411 Human
  UniProt ID Q96EB6
• Background: This gene encodes a member of the sirtuin family of proteins,homologs to the yeast Sir2 protein.Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes.The functions of human sirtuins have not yet been determined;however,yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.The protein encoded by this gene is included in class I of the sirtuin family.Alternative splicing results in multiple transcript variants. [provided by RefSeq,Dec 2008]
• Synonyms: SIR2; SIR2alpha; SIR2L1

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors