Hsp60 (HSPD1) Mouse Monoclonal Antibody [Clone ID: 6C8-G1-B10]

CAT#: TA346968

Mouse Monoclonal Hsp60 Antibody

Specifications

Product Data

• Clone Name: 6C8-G1-B10
• Applications: IF, IP, WB
• Recommended Dilution: WB: 1:1000, IF: 1:100, IP: 1:100
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: The immunogen for HSP60 antibody: purified recombinant human Hsp60 protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 60 kDa
• Gene Name: heat shock protein family D (Hsp60) member 1
• Database Link:
  NP_002147
  Entrez Gene 15510 MouseEntrez Gene 63868 RatEntrez Gene 3329 Human
  UniProt ID P10809
• Background: This gene encodes a member of the chaperonin family.The encoded mitochondrial protein may function as a signaling molecule in the innate immune system.This protein is essential for the folding and assembly of newly imported proteins in the mitochondria.This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter.Several pseudogenes have been associated with this gene.Two transcript variants encoding the same protein have been identified for this gene.Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq,Jun 2010]
• Synonyms: CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: RNA degradation, Type I diabetes mellitus