Myeloperoxidase(MPO) Rabbit Polyclonal Antibody
Rabbit Polyclonal Anti-MPO Antibody
Product Datasheet for 'TA343091'
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|Reactivity||Rabbit, Human, Rat, Mouse, Pig, Guinea pig, Dog, Goat, Bovine, Horse|
|Immunogen||The immunogen for anti-MPO antibody: synthetic peptide directed towards the N terminal of human MPO. Synthetic peptide located within the following region: QLNVLSKSSGCAYQDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVR|
|Formulation||Shipped as lyophilized powder. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Predicted Protein Size||84kDa|
|Background||Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.|
|Note||Immunogen Sequence Homology: Human: 100%; Rabbit: 100%; Rat: 93%; Pig: 86%; Mouse: 86%; Guinea pig: 86%; Dog: 83%; Goat: 79%; Horse: 79%; Bovine: 79%|
|Protein Families||Druggable Genome|