HIRA Rabbit Polyclonal Antibody

CAT#: TA342261

Rabbit Polyclonal Anti-Hira Antibody

Product Images

WB Suggested Anti-Hira Antibody Titration: 0.2-1 ug/ml; Positive Control: Mouse Brain

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Hira antibody: synthetic peptide directed towards the middle region of mouse Hira. Synthetic peptide located within the following region: LRSRELESSSDSDEKVHLAKPSSLSKRKLELEVETVEKKKKGRPRKDSRL
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 112 kDa
• Gene Name: histone cell cycle regulator
• Database Link:
  NP_003316
  Entrez Gene 15260 Mouse
  UniProt ID P54198
• Background: Hira is required for the periodic repression of histone gene transcription during the cell cycle.Hira cooperates with ASF1A to promote replication-independent chromatin assembly.Hira is required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
• Synonyms: DGCR1; TUP1; TUPLE1
• Note: Immunogen Sequence Homology: Rat: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Guinea pig: 93%; Human: 86%; Dog: 79%; Horse: 79%

Reference Data

• Protein Families: Transcription Factors