IL17E (IL25) Mouse Monoclonal Antibody [Clone ID: 8B1]

CAT#: TA337154

Mouse Monoclonal IL-17E/IL-25 Antibody (8B1)

Product Images

Flow Cytometry: IL-17E/IL-25 Antibody (8B1) TA337154 - Intracellular analysis of IL-17E in PC3 cells using 1 ug of IL-17E antibody (green histogram represents isotype control antibody this antibody , red represents IL-17E antibody. this antibody was used for this test, and an anti-mouse IgG PE conjugated secondary antibody this antibody .

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  Western Blot: IL-17E/IL-25 Antibody (8B1) TA337154 - Analysis of IL17E in full-length recombinant protein using IL17E antibody at 0.5 ug/ml.

Specifications

Product Data

• Clone Name: 8B1
• Applications: FC, WB
• Recommended Dilution: Western Blot: 0.5-2ug/ml, Flow Cytometry: 1-2ug/ml
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Full-length human IL17E recombinant protein was used as the immunogen for this antibody.
• Formulation: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 25
• Database Link:
  NP_758525
  Entrez Gene 64806 Human
  UniProt ID Q9H293
• Background: As a member of the IL-17 family, IL-25 has been identified as a pro-inflammatory cytokine which is produced by Th17 effector cells thus enabling the TH17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis (1-3). IL-25 appears to stimulate IL-8 production and itself appears to be activated through IL-23, IL-6, and TGF-Beta (1). Studies of IL-25 expression and activation through NF-kB taken together with IL-17 production and Th17 polarization through TLR ligand activation further closely tie the IL-17 and Th17 family together with the TLR signaling network initiating and controlling immune responses (4-7).
• Synonyms: IL17E

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction