Lin28 (LIN28A) Rabbit Polyclonal Antibody

CAT#: TA336788

Rabbit Polyclonal LIN-28A Antibody

Product Images

Immunocytochemistry/Immunofluorescence: LIN-28A Antibody TA336788 - Analysis of LIN28 in NTERA-2 cells using TA336788. Nuclei (Blue) are counterstained using Hoechst 33258.

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  Immunohistochemistry: LIN-28A Antibody TA336788 - Analysis of LIN28 in E17.5 mouse embryo.

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  Western Blot: LIN-28A Antibody TA336788 - Analysis of LIN28 in NTERA-2 cell lysate.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: Immunohistochemistry: 1:1000, Immunocytochemistry/ Immunofluorescence: 10-15 ug/ml, Western Blot: 1:1000, Immunohistochemistry-Paraffin: 1:1000
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Partial recombinant human Lin28 protein expressed in E. coli. [Swiss-Prot# Q9H9Z2]
• Formulation: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Whole antisera
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: lin-28 homolog A
• Database Link:
  NP_078950
  Entrez Gene 83557 MouseEntrez Gene 79727 Human
  UniProt ID Q9H9Z2
• Background: Lin28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Lin28 is a marker of undifferentiated human embryonic stem cells and has been used to enhance the efficiency of the formation of induced pluripotent stem (iPS) cells from human fibroblasts. Lin28 has also been shown to bind to the let-7 pre-miRNA and block production of the mature let-7 microRNA in mouse embryonic stem cells.
• Synonyms: CSDD1; LIN-28; lin-28A; LIN28; ZCCHC1
• Note: This Lin28 antibody is useful for IHC-P, ICC/IF and Western blot.

Reference Data

• Protein Families: Transcription Factors