HAT1 Rabbit Polyclonal Antibody

CAT#: TA332983

Rabbit anti-HAT1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using HAT1 antibody.

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  Immunofluorescence analysis of U2OS cell using HAT1 antibody.

Specifications

Product Data

• Applications: ChIP, ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:50 - 1:200;ChIP 1:20 - 1:100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human HAT1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 419
• Gene Name: histone acetyltransferase 1
• Database Link:
  NP_001028257
  Entrez Gene 107435 MouseEntrez Gene 296501 RatEntrez Gene 8520 Human
  UniProt ID O14929
• Background: The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
• Synonyms: histone acetyltransferase 1; KAT1

Reference Data

• Protein Families: Druggable Genome