PGP9.5 (UCHL1) Rabbit Polyclonal Antibody

CAT#: TA327726

Rabbit Polyclonal PGP 9.5 Antibody

Product Images

Immunohistochemistry staining of Paraffin Nerve tissue tissue by PGP 9.5 antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 1:100 - 1:500
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ubiquitin C-terminal hydrolase L1
• Database Link:
  NP_004172
  Entrez Gene 7345 Human
  UniProt ID P09936
• Synonyms: HEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1
• Note: Protein gene product 9.5 (PGP 9.5), also known as ubiquitin carboxyl-terminal hydrolase-1 (UCHL-1), is a 27 kDa protein originally isolated from whole brain extracts. Although PGP 9.5 expression in normal tissues was originally felt to be strictly confined to neurons and neuroendocrine cells, it has been subsequently documented in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. LK Campbell et al. demonstrated immunostaining of a plethora of different mesenchymal neoplasms with this antibody.

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Parkinson's disease